Rarely, a normal spleen may be seen in the left upper quadrant, and an accessory spleen may be mobile and wander. You need to get 100% to score the 10 points available. Get started! The spleen is soft, highly vascular and dark purple in colour. Game Statistics. The human spleen is surrounded by a capsule of dense connective tissue containing relatively little muscle and therefore incapable of the extensive contraction exhibited by the muscular capsule of the spleen in dogs and cats. A rich branching network of trabeculae from the internal capsular surface subdivides the organ into communicating compartments. View as Printable Worksheet. Advertisement. The marginal zone contained large … Spleen; The human spleen is located in the upper left abdomen, behind the stomach. If there are clearly delimited anehogenic formations with distal acoustical amplification, it is necessary to differentiate: Polycystic (cysts may be multiple). Actions. This function, in combination with a highly organized lymphoid compartment, makes the spleen the most important organ for antibacterial and antifungal immune reactivity. Below is information about the structure and function of the canine spleen. Information on the anatomy of the spleen can be found on our sister website. Learn about its function, location in the body, and conditions that can affect the spleen. The "stuff" is first the Capsule, indicated by the black arrows that covers the whole organ. • Wedge shaped 2. We will tell you about the general structure of the spleen, how the spleen works in dogs, common diseases that affect the spleen and common diagnostic tests performed in dogs to evaluate the spleen. Gesche Tallen, Last modification: 2016/12/06 Table of contents. The spleen is divided by function and structure into the red pulp (RP) and white pulp (WP); in between these two regions is the marginal zone (MZ) in rodents and the perifollicular zone in humans (1, 2). WebMD's Spleen Anatomy Page provides a detailed picture, definition, and information about the spleen. Structure and function of the lymphatic system. The spleen is surrounded by a thin capsule covered by peritoneum (mesothelial cells). Add to New Playlist. • it lies between the fundus of the stomach and the diaphragm. The structure of the spleen enables it to remove older erythrocytes from the circulation and leads to the efficient removal of blood-borne microorganisms and cellular debris. The histological structure corresponds to that of the main spleen. Spleen histology slide (labeled) The spleen is a fist sized organ located in the left upper quadrant of the abdomen.It is the largest lymphoid organ and thus the largest filter of blood in the human body.The spleen has a unique location, embryological development and histological structure that differs significantly from other lymphoid organs. Many diseases and disorders of the spleen start with “Splen-” for example splenomegaly means enlargement of the spleen. Structure of the spleen. An introduction to the histology of the spleen, as presented by the University of Rochester Pathology IT Program Structure of the spleen in idiopathic thrombocytopenic purpura. The spleen combines the innate and adaptive immune system in a uniquely organized way. Author: Maria Yiallouros, erstellt am: 2016/11/30, Editor: Maria Yiallouros, English Translation: PD Dr. med. Full text Full text is available as a scanned copy of the original print version. Loading ... Add to tournament . Game Points. Normal Ultrasound (Equine) Histological section ©Nottingham Uni 2008 : The spleen lies vertically on the left side of the cranial abdomen. Rauscher spleen focus-forming virus contains functional gag and pol genes and a partially deleted env gene which is structurally related to the env genes of dual tropic murine leukemia viruses. Since the time of Hippocrates, it is believed that the spleen in the human body has a number of important functions. One of us! This function, in combination with a highly organized lymphoid compartment, makes the spleen the most important organ for antibacterial and antifungal immune reactivity. Spleen By: Muhammad Ramadan Ismael MBBCH Al-Azhar Faculty of Medicine, Cairo. 2. In principle, the presence of an accessory spleen does not represent any health risks. Whereas the spleen growth was limited compared to the body growth in embryonic stages, the relative spleen weight increased 2.8 fold during the first 4 weeks post-hatching in quail. The spleen is the largest lymphatic organ in the body. First of all notice how the over all organization of the spleen looks like a BIG MESS. The white pulp was characterized by the presence of large numbers of lymphatic nodules containing highly reactive germinal centers. Many diseases and disorders of the spleen start with “Splen-” for example splenomegaly means enlargement of the spleen. Spleen • Lymphatic organ connected to blood vascular system • Part of mononuclear phagocyte system. Spleen • situated principally in the left hypochondriac region, but its superior extremity extends into the epigastric region 3. Spleen. Add to favorites 1 favs. At the hilum, the capsule is thickened and sends trabeculae that run in the splenic parenchyma in different directions carrying along with them the blood vessels. Start studying 9. In many instances, the spleen enlarges as it performs its normal functions. The spleen is instead solely attached by its vascular pedicle and can become a wholly intraperitoneal hypermobile organ. It is multi-functional and to accommodate for this, it is a soft, vascularised organ with a fibro-elastic capsule. The word spleen comes from Ancient Greek σπλήν (splḗn). It is attached to the greater curvature of the stomach by the gastrosplenic ligament. The spleen is the largest single mass of lymphatic tissue in the body. Below is information about the structure and function of the canine spleen. The spleen is the largest organ of the lymphatic system.Located in the upper left region of the abdominal cavity, the spleen's primary function is to filter blood of damaged cells, cellular debris, and pathogens such as bacteria and viruses.Like the thymus, the spleen houses and aids in the maturation of immune system cells called lymphocytes. We will tell you about the general structure of the spleen, how the spleen works in dogs, common diseases that affect the spleen and common diagnostic tests performed in dogs to evaluate the spleen. Tavassoli M, McMillan R. The structure of the spleens of 12 patients with idiopathic thrombocytopenic purpura (ITP) who underwent splenectomy was studied. Structure and function of Spleen 1. Realistic illustration of structure of human spleen vector icon for on transparent background - Buy this stock vector and explore similar vectors at Adobe Stock It is necessary to investigate the area of the spleen gates for revealing tubular structures in varicose veins. Online quiz to learn Structure of the spleen; Your Skills & Rank. Histological structure of the spleen Stroma. The structure of the spleen enables it to remove older erythrocytes from the circulation and leads to the efficient removal of blood-borne microorganisms and cellular debris. Structure. Contents: • Anatomy • Physiology (Functions) • Splenic trauma • Splenomegaly 3. The spleen is an organ found in virtually all vertebrates. Location and Structure of Spleen: Spleen lies in between the fundus of the stom­ach and the diaphragm. Its average weight in the adult is about 150 gm. Well-delineated cystic formations. We have determined the co-crystal structures of spleen tyrosine kinase complexed with three known inhibitors: YM193306, a 7-azaindole derivative and R406. The physical organization of the spleen allows it to filter blood of pathogens and abnormal cells and facilitate … Structure and function of the immune system in the spleen Sci Immunol. Structures entering and leaving spleen at hilum: Splenic artery (branch of celiac artery) Splenic vein (branch of portal vein) Lymph vessels (efferent) Nerves; Blood moving through the spleen flows in sinusoids which contain distinct pores between endothelial cells. The pathologic process also may be acquired as a result of splenomegaly or ligamentous laxity, such as in pregnancy or muscular dystrophies. Disturbance of spleen echostructure with or without splenomegaly. Its long axis lies in the line of the tenth rib. 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